Tanah Haram Adalah
Labetalol Hcl Tablets
Labetalol Hcl Tablets Generic Name & Formulations General DescriptionLabetalol HCl 100mg, 200mg, 300mg; scored tabs.
Pharmacological ClassNoncardioselective beta-blocker/alpha-1 blocker.
How SuppliedContact supplier.
Labetalol Hcl Tablets Indications IndicationsHypertension.
Labetalol Hcl Tablets Dosage and Administration AdultIndividualize. Initially 100mg twice daily. Titrate at 2–3 day intervals in increments of 100mg twice daily. Usual maintenance: 200–400mg twice daily; max 2.4g/day.
ChildrenNot recommended.
Labetalol Hcl Tablets Contraindications ContraindicationsAsthma. 2nd- or 3rd-degree AV block. Overt cardiac failure. Cardiogenic shock. Severe bradycardia, other conditions associated with prolonged or severe hypotension.
Labetalol Hcl Tablets Boxed WarningsNot Applicable
Labetalol Hcl Tablets Warnings/Precautions Warnings/PrecautionsHistory of heart failure; withdraw gradually if cardiac failure continues despite adequate digitalization and diuretic. Monitor hepatic function; discontinue at first sign of liver injury. COPD. Pheochromocytoma. Diabetes. Surgery. Avoid abrupt cessation (ischemic heart disease may be exacerbated). Elderly. Pregnancy (Cat.C). Nursing mothers.
Labetalol Hcl Tablets PharmacokineticsSee Literature
Labetalol Hcl Tablets Interactions InteractionsCaution with verapamil. Potentiates hypotension with nitroglycerin. May block epinephrine, β-agonist bronchodilators. Adjust antidiabetic medication. Potentiated by cimetidine. Tremor with tricyclic antidepressants. Synergism with halothane; do not use high concentrations.
Labetalol Hcl Tablets Adverse Reactions Adverse ReactionsDizziness, GI upset, fatigue, nasal stuffiness, ejaculation failure, headache, dyspnea, vertigo, rash, orthostatic hypotension, edema, heart failure, bronchospasm, jaundice.
Labetalol Hcl Tablets Clinical TrialsSee Literature
Labetalol Hcl Tablets Note NotesFormerly known under the brand names Normodyne, Trandate.
Labetalol Hcl Tablets Patient CounselingSee Literature
Toprol-xl
Toprol-xl Generic Name & Formulations General DescriptionMetoprolol succinate 25mg, 50mg, 100mg, 200mg; scored ext-rel tabs.
Pharmacological ClassBeta-blocker.
How SuppliedTabs—100, 1000
How SuppliedToprol-XL Tablets are supplied in 100- and 1000-count bottles in the following strengths:
25 mg: white, biconvex, film-coated, oval, scored tablets engraved with "A/β"
50 mg: white, biconvex, film-coated, round, scored tablets engraved with "A/mo"
100 mg: white, biconvex, film-coated, round, scored tablets engraved with "A/ms"
200 mg: white, biconvex, film-coated, oval, scored tablets engraved with "A/mY"
Metoprolol is a β1-selective (cardioselective) adrenergic receptor blocking agent that slows the sinus rate and decreases AV nodal conduction. The β-blocking activity of metoprolol has been shown by reduction in heart rate and cardiac output at rest and upon exercise, reduction of systolic blood pressure upon exercise, inhibition of isoproterenol-induced tachycardia, and reduction of reflex orthostatic tachycardia.
Toprol-xl Indications IndicationsAngina pectoris.
Toprol-xl Dosage and Administration AdultInitially 100mg once daily. May increase at 1-week intervals; max 400mg/day.
ChildrenNot established.
Toprol-xl Contraindications ContraindicationsSevere bradycardia. 2nd- or 3rd-degree heart block. Cardiogenic shock. Decompensated heart failure. Sick sinus syndrome (unless paced).
Toprol-xl Boxed WarningsNot Applicable
Toprol-xl Warnings/Precautions Warnings/PrecautionsMild or compensated heart failure. Ischemic heart or peripheral vascular disease. 1st-degree AV block. Sinus node dysfunction. Conduction disorders (eg, Wolff-Parkinson-White). Monitor HR during therapy. Bronchospastic disease. Pheochromocytoma. Surgery. Diabetes. May mask signs and increase risk for hypoglycemia. Hyperthyroidism. Avoid abrupt cessation. Hepatic impairment. Elderly. Neonates. Pregnancy. Nursing mothers: monitor infants.
Warnings/PrecautionsAbrupt Cessation of Therapy
Avoid abruptly discontinuing Toprol-XL in patients treated only for hypertension.
When discontinuing chronically administered Toprol-XL especially in patients with ischemic heart disease, gradually reduce the dose of Toprol-XL over a period of 1 to 2 weeks and monitor the patient.
Immediately reinstate Toprol-XL if angina worsens or acute coronary ischemia develops, and appropriately manage unstable angina. Advise patients not to interrupt therapy without consulting a physician.
Heart Failure
While up-titration, worsening cardiac failure may occur. If these symptoms occur, then increase diuretics and restore clinical stability prior to advancing the dose of Toprol-XL.
Consider lowering the dose of Toprol-XL or temporarily discontinuing it.
Bronchospastic Disease
In general, do not give beta-blockers to patients with bronchospastic disease.
Toprol-XL may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. Use the lowest possible dose of Toprol-XL.
Have bronchodilators, including beta2-agonists, readily available or administered concomitantly.
Bradycardia
Bradycardia, including sinus pause, heart block, and cardiac arrest have occurred with the use of Toprol-XL.
Increased risk for bradycardia in patients with first-degree AV block, sinus node dysfunction, conduction disorders (including Wolff-Parkinson-White) or on concomitant drugs.
Monitor heart rate. Discontinue or reduce dose of Toprol-XL if severe bradycardia occurs.
Pheochromocytoma
Administer with an alpha-blocker and only after the alpha-blocker has been initiated if Toprol-XL is used in the setting of pheochromocytoma.
Administration of beta-blockers alone in the setting of pheochromocytoma may cause a paradoxical increase in BP.
Major Surgery
Avoid initiating a high-dose regimen of metoprolol extended-release in patients undergoing non-cardiac surgery, since such use in patients with cardiovascular risk factors has been associated with bradycardia, hypotension, stroke, and death.
Do not routinely withdraw chronically administered beta-blocking therapy prior to major surgery.
Hypoglycemia
May prevent early warning signs of hypoglycemia (eg, tachycardia) and increased risk for severe or prolonged hypoglycemia especially in patients with diabetes mellitus or children who are fasting.
Seek emergency treatment if severe hypoglycemia occurs.
Thyrotoxicosis
May mask certain clinical signs of hyperthyroidism, (eg, tachycardia). Abrupt withdrawal may precipitate a thyroid storm.
Peripheral Vascular Disease
Anaphylactic Reaction
While taking beta-blockers, patients with a history of severe anaphylactic reactions to a variety of allergens may be more reactive to repeated challenge and may be unresponsive to the usual doses of epinephrine used to treat an allergic reaction.
Risk Summary
Available data from published observational studies have not demonstrated a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes with metoprolol use during pregnancy.
Clinical Consideration
Fetal/Neonatal adverse reactions: Metoprolol crosses the placenta. Neonates born to mothers who are receiving metoprolol during pregnancy, may be at risk for hypotension, hypoglycemia, bradycardia, and respiratory depression. Observe neonates and manage accordingly.
Risk Summary
Limited available data from published literature report that metoprolol is present in human milk.
No adverse reactions of metoprolol on the breastfed infant have been identified. There is no information regarding the effects of metoprolol on milk production.
Clinical Consideration
Geriatric ConsiderationsThere were no notable differences in efficacy or the rate of adverse reactions between older and younger patients.
In general, use a low initial starting dose in elderly patients given their greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
No studies have been performed with Toprol-XL in patients with hepatic impairment.
Poor hepatic function is most likely to increase blood levels of metoprolol. In patients with impaired hepatic function, initiate Toprol-XL at doses lower than recommended and gradually increase the dose.
Females and Males of Reproductive Potential
Toprol-xl Pharmacokinetics DistributionMay potentiate hypotension or marked bradycardia with catecholamine depleting drugs (eg, reserpine, MAOIs). Potentiated by strong CYP2D6 inhibitors (eg, quinidine, fluoxetine, paroxetine, propafenone); monitor if unavoidable. Increased risk of bradycardia with glycosides, clonidine, diltiazem, verapamil. May block epinephrine.
Toprol-xl Adverse Reactions Adverse ReactionsFatigue, dizziness, depression, diarrhea, dyspnea, bradycardia, rash; heart block, MI, angina.
Toprol-xl Clinical Trials Clinical TrialsAngina Pectoris
Controlled clinical studies have shown that the immediate-release formulation of metoprolol at dosages of 100 to 400 mg once daily was effective as an antianginal agent, reducing the number of angina attacks and increasing exercise tolerance.
Not Applicable
Toprol-xl Patient CounselingSee Literature
Toprol-xl Generic Name & Formulations General DescriptionMetoprolol succinate 25mg, 50mg, 100mg, 200mg; scored ext-rel tabs.
Pharmacological ClassBeta-blocker.
How SuppliedTabs—100, 1000
How SuppliedToprol-XL Tablets are supplied in 100- and 1000-count bottles in the following strengths:
25 mg: white, biconvex, film-coated, oval, scored tablets engraved with "A/β"
50 mg: white, biconvex, film-coated, round, scored tablets engraved with "A/mo"
100 mg: white, biconvex, film-coated, round, scored tablets engraved with "A/ms"
200 mg: white, biconvex, film-coated, oval, scored tablets engraved with "A/mY"
Metoprolol is a β1-selective (cardioselective) adrenergic receptor blocking agent that slows the sinus rate and decreases AV nodal conduction. The β-blocking activity of metoprolol has been shown by reduction in heart rate and cardiac output at rest and upon exercise, reduction of systolic blood pressure upon exercise, inhibition of isoproterenol-induced tachycardia, and reduction of reflex orthostatic tachycardia.
Toprol-xl Indications IndicationsHeart failure, to reduce the risk of cardiovascular mortality and heart failure hospitalizations in patients with heart failure.
Toprol-xl Dosage and Administration AdultClass II: initially 25mg once daily; more severe: 12.5mg once daily. May double dose as tolerated every 2 weeks; reduce if symptomatic bradycardia occurs; max 200mg/day.
ChildrenNot established.
Toprol-xl Contraindications ContraindicationsSevere bradycardia. 2nd- or 3rd-degree heart block. Cardiogenic shock. Decompensated heart failure. Sick sinus syndrome (unless paced).
Toprol-xl Boxed WarningsNot Applicable
Toprol-xl Warnings/Precautions Warnings/PrecautionsMild or compensated heart failure. Ischemic heart or peripheral vascular disease. 1st-degree AV block. Sinus node dysfunction. Conduction disorders (eg, Wolff-Parkinson-White). Monitor HR during therapy. Bronchospastic disease. Pheochromocytoma. Surgery. Diabetes. May mask signs and increase risk for hypoglycemia. Hyperthyroidism. Avoid abrupt cessation. Hepatic impairment. Elderly. Neonates. Pregnancy. Nursing mothers: monitor infants.
Warnings/PrecautionsAbrupt Cessation of Therapy
Avoid abruptly discontinuing Toprol-XL in patients treated only for hypertension.
When discontinuing chronically administered Toprol-XL especially in patients with ischemic heart disease, gradually reduce the dose of Toprol-XL over a period of 1 to 2 weeks and monitor the patient.
Immediately reinstate Toprol-XL if angina worsens or acute coronary ischemia develops, and appropriately manage unstable angina. Advise patients not to interrupt therapy without consulting a physician.
Heart Failure
While up-titration, worsening cardiac failure may occur. If these symptoms occur, then increase diuretics and restore clinical stability prior to advancing the dose of Toprol-XL.
Consider lowering the dose of Toprol-XL or temporarily discontinuing it.
Bronchospastic Disease
In general, do not give beta-blockers to patients with bronchospastic disease.
Toprol-XL may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. Use the lowest possible dose of Toprol-XL.
Have bronchodilators, including beta2-agonists, readily available or administered concomitantly.
Bradycardia
Bradycardia, including sinus pause, heart block, and cardiac arrest have occurred with the use of Toprol-XL.
Increased risk for bradycardia in patients with first-degree AV block, sinus node dysfunction, conduction disorders (including Wolff-Parkinson-White) or on concomitant drugs.
Monitor heart rate. Discontinue or reduce dose of Toprol-XL if severe bradycardia occurs.
Pheochromocytoma
Administer with an alpha-blocker and only after the alpha-blocker has been initiated if Toprol-XL is used in the setting of pheochromocytoma.
Administration of beta-blockers alone in the setting of pheochromocytoma may cause a paradoxical increase in BP.
Major Surgery
Avoid initiating a high-dose regimen of metoprolol extended-release in patients undergoing non-cardiac surgery, since such use in patients with cardiovascular risk factors has been associated with bradycardia, hypotension, stroke, and death.
Do not routinely withdraw chronically administered beta-blocking therapy prior to major surgery.
Hypoglycemia
May prevent early warning signs of hypoglycemia (eg, tachycardia) and increased risk for severe or prolonged hypoglycemia especially in patients with diabetes mellitus or children who are fasting.
Seek emergency treatment if severe hypoglycemia occurs.
Thyrotoxicosis
May mask certain clinical signs of hyperthyroidism, (eg, tachycardia). Abrupt withdrawal may precipitate a thyroid storm.
Peripheral Vascular Disease
Anaphylactic Reaction
While taking beta-blockers, patients with a history of severe anaphylactic reactions to a variety of allergens may be more reactive to repeated challenge and may be unresponsive to the usual doses of epinephrine used to treat an allergic reaction.
Risk Summary
Available data from published observational studies have not demonstrated a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes with metoprolol use during pregnancy.
Clinical Consideration
Fetal/Neonatal adverse reactions: Metoprolol crosses the placenta. Neonates born to mothers who are receiving metoprolol during pregnancy, may be at risk for hypotension, hypoglycemia, bradycardia, and respiratory depression. Observe neonates and manage accordingly.
Risk Summary
Limited available data from published literature report that metoprolol is present in human milk.
No adverse reactions of metoprolol on the breastfed infant have been identified. There is no information regarding the effects of metoprolol on milk production.
Clinical Consideration
Geriatric ConsiderationsThere were no notable differences in efficacy or the rate of adverse reactions between older and younger patients.
In general, use a low initial starting dose in elderly patients given their greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
No studies have been performed with Toprol-XL in patients with hepatic impairment.
Poor hepatic function is most likely to increase blood levels of metoprolol. In patients with impaired hepatic function, initiate Toprol-XL at doses lower than recommended and gradually increase the dose.
Females and Males of Reproductive Potential
Toprol-xl Pharmacokinetics DistributionMay potentiate hypotension or marked bradycardia with catecholamine depleting drugs (eg, reserpine, MAOIs). Potentiated by strong CYP2D6 inhibitors (eg, quinidine, fluoxetine, paroxetine, propafenone); monitor if unavoidable. Increased risk of bradycardia with glycosides, clonidine, diltiazem, verapamil. May block epinephrine.
Toprol-xl Adverse Reactions Adverse ReactionsFatigue, dizziness, depression, diarrhea, dyspnea, bradycardia, rash; heart block, MI, angina.
Toprol-xl Clinical Trials Clinical TrialsHeart Failure
The randomized, double-blind, placebo-controlled MERIT-HF study evaluated the efficacy of Toprol-XL in 3991 patients with ejection fraction ≤0.40 and NYHA Class II-IV heart failure attributable to ischemia, hypertension, or cardiomyopathy. Patients were randomly assigned 1:1 to receive Toprol-XL or placebo. The primary endpoints of the trial were (1) all-cause mortality plus all-cause hospitalization (time to first event) and (2) all-cause mortality.
The trial was terminated early for a statistically significant reduction in all-cause mortality (34%, nominal P =.00009).
The risk of all-cause mortality plus all-cause hospitalization was reduced by 19% (P =.00012). The trial also showed improvements in heart failure-related mortality and heart failure-related hospitalizations, and NYHA functional class.
Not Applicable
Toprol-xl Patient CounselingSee Literature
Toprol-xl Generic Name & Formulations General DescriptionMetoprolol succinate 25mg, 50mg, 100mg, 200mg; scored ext-rel tabs.
Pharmacological ClassCardioselective beta-blocker.
How SuppliedTabs—100, 1000
How SuppliedToprol-XL Tablets are supplied in 100- and 1000-count bottles in the following strengths:
25 mg: white, biconvex, film-coated, oval, scored tablets engraved with "A/β"
50 mg: white, biconvex, film-coated, round, scored tablets engraved with "A/mo"
100 mg: white, biconvex, film-coated, round, scored tablets engraved with "A/ms"
200 mg: white, biconvex, film-coated, oval, scored tablets engraved with "A/mY"
Metoprolol is a β1-selective (cardioselective) adrenergic receptor blocking agent that slows the sinus rate and decreases AV nodal conduction. The β-blocking activity of metoprolol has been shown by reduction in heart rate and cardiac output at rest and upon exercise, reduction of systolic blood pressure upon exercise, inhibition of isoproterenol-induced tachycardia, and reduction of reflex orthostatic tachycardia.
Toprol-xl Indications IndicationsHypertension.
Toprol-xl Dosage and Administration AdultInitially 25–100mg once daily, alone or with a diuretic. May increase at 1-week intervals; max 400mg/day.
Children<6yrs: not established. ≥6yrs: initially 1mg/kg once daily; max 50mg/day. Adjust based on response. Max 2mg/kg (200mg) daily.
Toprol-xl Contraindications ContraindicationsSevere bradycardia. 2nd- or 3rd-degree heart block. Cardiogenic shock. Decompensated heart failure. Sick sinus syndrome (unless paced).
Toprol-xl Boxed WarningsNot Applicable
Toprol-xl Warnings/Precautions Warnings/PrecautionsMild or compensated heart failure. Ischemic heart or peripheral vascular disease. 1st-degree AV block. Sinus node dysfunction. Conduction disorders (eg, Wolff-Parkinson-White). Monitor HR during therapy. Bronchospastic disease. Pheochromocytoma. Surgery. Diabetes. May mask signs and increase risk for hypoglycemia. Hyperthyroidism. Avoid abrupt cessation. Hepatic impairment. Elderly. Neonates. Pregnancy. Nursing mothers: monitor infants.
Warnings/PrecautionsAbrupt Cessation of Therapy
Avoid abruptly discontinuing Toprol-XL in patients treated only for hypertension.
When discontinuing chronically administered Toprol-XL especially in patients with ischemic heart disease, gradually reduce the dose of Toprol-XL over a period of 1 to 2 weeks and monitor the patient.
Immediately reinstate Toprol-XL if angina worsens or acute coronary ischemia develops, and appropriately manage unstable angina. Advise patients not to interrupt therapy without consulting a physician.
Heart Failure
While up-titration, worsening cardiac failure may occur. If these symptoms occur, then increase diuretics and restore clinical stability prior to advancing the dose of Toprol-XL.
Consider lowering the dose of Toprol-XL or temporarily discontinuing it.
Bronchospastic Disease
In general, do not give beta-blockers to patients with bronchospastic disease.
Toprol-XL may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. Use the lowest possible dose of Toprol-XL.
Have bronchodilators, including beta2-agonists, readily available or administered concomitantly.
Bradycardia
Bradycardia, including sinus pause, heart block, and cardiac arrest have occurred with the use of Toprol-XL.
Increased risk for bradycardia in patients with first-degree AV block, sinus node dysfunction, conduction disorders (including Wolff-Parkinson-White) or on concomitant drugs.
Monitor heart rate. Discontinue or reduce dose of Toprol-XL if severe bradycardia occurs.
Pheochromocytoma
Administer with an alpha-blocker and only after the alpha-blocker has been initiated if Toprol-XL is used in the setting of pheochromocytoma.
Administration of beta-blockers alone in the setting of pheochromocytoma may cause a paradoxical increase in BP.
Major Surgery
Avoid initiating a high-dose regimen of metoprolol extended-release in patients undergoing non-cardiac surgery, since such use in patients with cardiovascular risk factors has been associated with bradycardia, hypotension, stroke, and death.
Do not routinely withdraw chronically administered beta-blocking therapy prior to major surgery.
Hypoglycemia
May prevent early warning signs of hypoglycemia (eg, tachycardia) and increased risk for severe or prolonged hypoglycemia especially in patients with diabetes mellitus or children who are fasting.
Seek emergency treatment if severe hypoglycemia occurs.
Thyrotoxicosis
May mask certain clinical signs of hyperthyroidism, (eg, tachycardia). Abrupt withdrawal may precipitate a thyroid storm.
Peripheral Vascular Disease
Anaphylactic Reaction
While taking beta-blockers, patients with a history of severe anaphylactic reactions to a variety of allergens may be more reactive to repeated challenge and may be unresponsive to the usual doses of epinephrine used to treat an allergic reaction.
Risk Summary
Available data from published observational studies have not demonstrated a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes with metoprolol use during pregnancy.
Clinical Consideration
Fetal/Neonatal adverse reactions: Metoprolol crosses the placenta. Neonates born to mothers who are receiving metoprolol during pregnancy, may be at risk for hypotension, hypoglycemia, bradycardia, and respiratory depression. Observe neonates and manage accordingly.
Risk Summary
Limited available data from published literature report that metoprolol is present in human milk.
No adverse reactions of metoprolol on the breastfed infant have been identified. There is no information regarding the effects of metoprolol on milk production.
Clinical Consideration
Geriatric ConsiderationsThere were no notable differences in efficacy or the rate of adverse reactions between older and younger patients.
In general, use a low initial starting dose in elderly patients given their greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
No studies have been performed with Toprol-XL in patients with hepatic impairment.
Poor hepatic function is most likely to increase blood levels of metoprolol. In patients with impaired hepatic function, initiate Toprol-XL at doses lower than recommended and gradually increase the dose.
Females and Males of Reproductive Potential
Toprol-xl Pharmacokinetics DistributionMay potentiate hypotension or marked bradycardia with catecholamine depleting drugs (eg, reserpine, MAOIs). Potentiated by strong CYP2D6 inhibitors (eg, quinidine, fluoxetine, paroxetine, propafenone); monitor if unavoidable. Increased risk of bradycardia with glycosides, clonidine, diltiazem, verapamil. May block epinephrine.
Toprol-xl Adverse Reactions Adverse ReactionsFatigue, dizziness, depression, diarrhea, dyspnea, bradycardia, rash; heart block, MI, angina.
Toprol-xl Clinical Trials Clinical TrialsHypertension
A double-blind study evaluated the efficacy of Toprol-XL in 1092 patients with mild to moderate hypertension. Patients were randomly assigned to receive once daily Toprol-XL (25, 100, or 400 mg), Plendil (felodipine extended-release tablets), the combination, or placebo. Results showed that treatment with Toprol-XL alone decreased sitting BP by 6–8/4–7 mmHg (placebo-corrected change from baseline) at 24 hours post-dose after 9 weeks. The combination of Toprol-XL and Plendil had greater effects on BP.
In controlled clinical studies, an immediate-release dosage form of metoprolol (100–450 mg daily) achieved effective antihypertensive effects when used alone or as concomitantly with thiazide-type diuretics. Toprol-XL at dosages of 100–400 mg once daily had similar results as conventional metoprolol tablets administered 2 to 4 times daily. Moreover, Toprol-XL 50 mg once daily lowered blood pressure 24 hours post-dosing in placebo-controlled studies.
In controlled, comparative clinical studies, immediate-release dosage form of metoprolol was observed to be comparable to propranolol, methyldopa, and thiazide-type diuretics, and affected both supine and standing BP.
Not Applicable
Toprol-xl Patient CounselingSee Literature
From Omega Oil To Cholesterol Tablets, We Test Three Ways To Look After Your Heart
CARDIOVASCULAR disease is the UK's leading cause of mortality among women.
It kills one in 14 a year – around 2.5million – making it ten times deadlier than breast cancer.
4
We look at three ways to look after your heartBut there are things you can do to look after your heart.
Exercise, a Mediterranean diet, checking cholesterol and blood pressure monitoring can all help.
Today, Jane Atkinson looks at how best to care for your ticker. . .
OMEGA 3 OIL4
A lack of omega 3 is linked to depression and an increase in belly fatCredit: SUPPLIEDABOUT 98 per cent of adults don't have enough omega 3 in their bodies.
These essential fats are an energy source, keep your heart healthy and also help with lung health and immunity.
A lack of omega 3 is linked to depression and an increase in belly fat.
The body can't make these fats so you need two to three portions of fish a week, or a supplement.
Osavi have just launched a range of high-quality, marine fish oil supplements from Norway.
Most read in Health
HARD TO SWALLOW
Multivitamins could increase risk of killer disease by 30%, charity warns
NEW FEAR
Warning as outbreak of deadly Victorian disease declared as 7 children fall ill
GUT FEELS
You should eat 30 plants weekly for good health - 7 surprising foods that count
DRUG DEAL
Common antibiotics 'no longer effective' in children - fuelling surge in deathsI tried a teaspoon a day of the lemon-mint flavour, which you have to knock back.
It doesn't have enough of a flavour to mask the oil and the texture is tricky as it sticks around your mouth but, at the end of the day, it is only a small spoon of oil you're taking.
If you don't like pills, this is a great option. £17.20 on Amazon.
See osavi.Com.
CUT CHOLESTEROL4
These Plant Sterols are clinically proven supplements to help reduce cholesterolHEALTHSPAN's Plant Sterols are clinically proven supplements to help reduce cholesterol.
Figures from the British Heart Foundation have revealed that more younger people are being diagnosed with high cholesterol.
Levels of non-HDL, or "bad cholesterol", in the blood are closely linked to risk of coronary heart disease.
These sterols can lower cholesterol by up to 12 per cent without any side effects.
Each tablet supplies 800mg of sterols so I knocked back three to get the 2,400mg recommended per day.
Because sterols work in a different way to statin drugs, the two can be used together to lower cholesterol levels even further.
Healthspan Plant Sterols – 90 capsules, £15.95, healthspan.Co.Uk.
MONITOR RATE4
The Polar OH1+ can be worn on your arm to monitor your heart rateCredit: suppliedIF YOU want to check your heart rate in real time or keep a record of it, you need a heart rate monitor.
Polar has straps that go around the chest but with the dinky new Polar OH1+ you can pop it on your arm with an armband.
It's waterproof and can clip to your goggles when swimming to get your heart rate through your temple.
You can use it as a standalone device or pair it with various fitness apps, sports watches and smart watches, thanks to Bluetooth and ANT+ connectivity.
It has 6-LED optical heart rate solution and its built-in memory can store up to 200 hours of data.
I loved this.
Accurate data and it lost connection with my watch for just one second on a 45-minute run. £51.50, polar.Com/uk-en.
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