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Showing posts from July, 2021

FCA upholds award of compound interest in Cefaclor damages appeal - Lexology

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In the latest Cefaclor decision, the Federal Court of Appeal has upheld the award of compound interest as damages for the time value of money lost, where there is trial evidence to support the award.[1] As one of the longest running intellectual property cases in Canada, the history of the case is lengthy and complex. The nearly 25-year legal battle stems from an action for patent infringement commenced by Eli Lilly and Company and Eli Lilly Canada Inc. (collectively, "Lilly") against Apotex Inc. ("Apotex") in June 1997 with respect to the cefaclor antibiotic drug product. Approximately 12 years later, the liability judgment found that each of the eight patents at issue were infringed by Apotex.[2] The liability judgment was upheld by the Federal Court of Appeal,[3] and following an unsuccessful leave to appeal to the Supreme Court of Canada,[4] the determination of remedies fell to the Federal Court. The trial for the damages reference took place in 2014, and r...

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2 - Science Magazine

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Screening for drugs that don't work In the battle against COVID-19, drugs discovered in repurposing screens are of particular interest because these could be rapidly implemented as treatments. However, Tummino et al. deliver a cautionary tale, finding that many leads from such screens have an antiviral effect in cells through phospholipidosis, a phospholipid storage disorder that can be induced by cationic amphiphilic drugs (see the Perspective by Edwards and Hartung). There is a strong correlation between drug-induced phospholipidosis and inhibition of severe acute respiratory syndrome coronavirus 2 replication in cells. Unfortunately, drugs that have an antiviral effect in cells through phospholipidosis are unlikely to be effective in vivo. Screening out such drugs may allow a focus on drugs with better clinical potential. Science , abi4708, this issue p. 541; see also abj9488, p. 488 Abstract Repurposing drugs as treatments for COVID-19, the disease caused by severe acute respi...

North Dakota will start to open the 'black box' on prescription drug prices with new transparency law - Park Rapids Enterprise

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Fancy foods and a family's pharmacy in Montclair (Robin's Nest) - Montclair Local

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Casa Firelli Hot Sauce Sauce, a product from Montclairian Elwyn Gladstone's company, is ready to use on pizza, pasta or as a seasoning. (Courtesy Elwyn Gladstone) By ROBIN WOODS For Montclair Local It's summertime, my favorite time of the year — warm hands, warm feet and a warm glow on my face and arms from being outside in the sun as often as possible. I won't be traveling this year, but I discovered new businesses and products distributed right here in town that warm my heart and my taste buds. I chatted with Elwyn Gladstone, founder and owner of biggarandleith.com, which owns and imports a portfolio of spirits and fancy foods from family-owned producers. He and his business partner, Mark Teasdale, create brands and find interesting companies to make them. Their office is located on Plymouth Street, where the magic begins, with Gladstone saying, "We each do things well, differently." Gladstone has lived in many places in his life, born in Boston and moving to En...

Delayed/extended-release methylphenidate improves children's control of ADHD symptoms - Healio

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July 13, 2021 2 min read Source/Disclosures Disclosures: Childress reports numerous relevant financial disclosures. Please see the study for her and all other authors' relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . " data-action="subscribe"> Subscribe ADDED TO EMAIL ALERTS We were unable to process your ...

Venlafaxine ER oral capsule: Side effects, dosage, and more - Medical News Today

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Here are answers to some frequently asked questions about venlafaxine ER oral capsule. Does venlafaxine cause weight gain or weight loss? Weight gain and weight loss weren't reported in people who took venlafaxine during clinical studies. However, adults who took venlafaxine during the studies commonly reported a loss of appetite. If you lose your appetite, it could lead to weight loss over time. Depression and anxiety disorders, which venlafaxine treats, often cause changes in appetite and eating patterns. And both can lead to either weight gain or weight loss. If you're concerned about weight gain or weight loss while you're taking venlafaxine, talk with your doctor. They can suggest ways to help you maintain a body weight that's healthy for you. Is venlafaxine used for hot flashes, migraine, or ADHD? Yes, venlafaxine is sometimes used for hot flashes, migraine, and attention deficit hyperactivity disorder (ADHD). But these are off-label uses for this drug. Off-label ...

Stores that will be open during the 4th of July - Fox Business

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Check out what's clicking on FoxBusiness.com. The Fourth of July lands on a Sunday this year, meaning most companies are taking Monday off to observe the holiday.  Luckily for consumers, most major retailers from Home Depot to Target will still remain open over the holiday weekend and in most cases, under normal business hours.  CLICK HERE TO READ MORE ON FOX BUSINESS However, one of the largest retailers, Costco, will be closed for Independence Day, the company confirmed to FOX Business.  Here is the list of some major namesakes that will remain open.  CVS: Many CVS Pharmacy locations, including 24 hours locations, will remain open with regular hours on July 4th and 5th, a spokesperson told FOX Business. However, pharmacy hours may be reduced or locations closed for the holiday. Customers should call ahead to their local store, or visiting cvs.com to confirm store and pharmacy hours. A c...

Rising Prevalence of Gastric Disorders Increasing the Sales in Nizatidine Market: Fact.MR - BioSpace

Initiatives undertaken to spread awareness about various disease driving the growth of the nizatidine market in developing countries Fact.MR - A Market Research and Competitive Intelligence Provider : The global nizatidine market is exhibiting a positive growth due to the increasing prevalence of gastric disorders such as Inflammatory Bowel Disease (IBD), constipation, hemorrhoids, stomach ulcers, etc. As per a study by Fact.MR – a leading market research and competitive intelligence provider, the market for nizatidine is anticipated to surge at a CAGR of over 9% during the forecast period 2021 to 2031. As per the British Medical Association (BMA), non-communicable diseases (NCDs) account for over 60% of the global ailments, with gastric problems encompassing the majority of this overall burden. Over 60 million people are suffering from various digestive ailments, resulting in the hospitalization of more than 1 million in the U.S., according to the National Institute of Di...

Humalog Side Effects: What They Are and How to Manage Them - Healthline

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If you have diabetes, your doctor might suggest Humalog (insulin lispro) as a treatment option for your condition. Along with other questions you may have about the drug, you could be wondering about its side effects. Humalog is a prescription medication that's used to help manage blood sugar in people with diabetes. There are two types of Humalog product: Humalog and Humalog Mix. Both types can be used in adults with type 1 or type 2 diabetes. Humalog can also be used in certain children with type 1 diabetes. Humalog is a rapid-acting insulin. You'll receive it by injection under your skin. (You can give yourself injections after your doctor shows you how.) Healthcare professionals in a hospital may sometimes give Humalog by injection into a vein. Humalog comes in these forms: prefilled disposable injection pens (Humalog KwikPen, Junior KwikPen, and Tempo pen) cartridges for use with reusable insulin pens vials for use with insulin syringes or insulin pumps (devices that conti...